If you want immediate results, then Troxiven does the job.
Other dietary supplements such as red grape extract, horse chestnut, grape seed extract, and type 3 collagen work to strengthen the tone of vein walls, but long-term results are seen after at least one month. Also, diosmin and bromelain (the latter on an empty stomach) work on thrombosis, but these substances also require long-term use.
However, Troxiven works differently. It acts hormonally and immediately (temporarily, though, as we need another pill every day). I tried it on my mother who has a serious walking problem (1.5 months now) with pain behind her knee due to venous insufficiency. Significant results from the first pill within an hour. We tried all the other substances in pills and teas with no immediate results (except maybe turmeric). With creams, we have low absorption and only local effects, so we didn't have significant results.

If someone doesn't have the money for the supplement, they can take hesperidin to have hesperidin intake. They can scrape the peel of about 4 teaspoons of orange, mix it with about 2 teaspoons of honey, and eat the mixture as a dessert.

"Diosmin is a semi-synthetic phlebotropic drug (modified hesperidin), a member of the flavonoid family. Diosmin prolongs the vasoconstrictive action of norepinephrine on the venous wall, resulting in increased venous tone and consequently a decrease in venous capacitance, distensibility, and stasis."

Source: Galen Pharmaceutical Guide

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I am providing below a Google Translate of the Troxiven instruction leaflet, which is in Italian:

Bioflavonoids - Hesperidin - Rutin - Folic Acid.
* Functional characteristics of the components
Diosmin: a natural flavonoid with strong veno-protective properties. It contributes to the resolution of inflammation in the venous and capillary system (phlebitis, internal and external hemorrhoids). Like all flavonoids, it also has diuretic and antispasmodic properties and also contributes to the preservation of vitamin C.
Hesperidin: it has the function of correcting the integrity and normal permeability of the capillary wall. It prevents red blood cells from leaving the blood circulation. Its deficiency can lead to the appearance of hemorrhages. It also has oxidoreductive abilities and intervenes in cellular respiration processes and carbohydrate metabolism, contributing to the reduction of glucose concentration in the plasma.
Rutin: A bioflavonoid with rheological, phlebotonic, and vascular protective properties. Rutin is a powerful antioxidant and has the ability to strengthen the capillary wall. It is also used for relief from symptoms due to lymphatic and venous circulation of the lower limbs, neutralizing edema.
Folic Acid: It is involved in the metabolism of certain amino acids, the formation of red blood cells, and the synthesis of nucleic acids. Folic acid is mainly used by rapidly growing tissues. In adults, its deficiency leads to an increased risk of ischemic heart disease.
INGREDIENTS: Diosmin, Hesperidin, Rutin. Hydroxypropylmethylcellulose; Bulking agent: Microcrystalline cellulose. Anti-caking agents: Vegetable stearic acid, titanium dioxide. Folic Acid.
DOSAGE: It is recommended to take 1 tablet per day. Packaging with 20 retard tablets of 1 g.
* You can consult the functional characteristics of the substances on the website with free access www.ncbi.nlm.nih.gov/pubmed/advanced and from international bibliographic references.
LEAFLET
PAP 22
PAPER COLLECTION
1 SEPARATE COLLECTION. CHECK THE ARRANGEMENTS (OF YOUR MUNICIPALITY.
Proprietary product
Euro-Pharma S.r.I., Via Garzigliana, 8 - 10127 Turin, Italy - [email protected]