Special Food Supplements

Doctor's Formulas D-Mannose Special Food Supplement 60 Capsules

Dietary supplement containing the monosaccharide D-mannose and bearberry extract. Mannose is used for urinary tract infections, such as cystitis, while bearberry contributes to the normal function of

Dietary supplement containing the monosaccharide D-mannose and bearberry extract. Mannose is used for urinary tract infections, such as cystitis, while bearberry contributes to the normal function of the urinary system and bladder. 

See full description See full description
  • Action Urinary
  • See all

Description

Description

Dietary supplement containing the monosaccharide D-mannose and bearberry extract. Mannose is used for urinary tract infections, such as cystitis, while bearberry contributes to the normal function of the urinary system and bladder. It helps in the prevention and relief of initial symptoms by preventing bacteria from adhering to the mucosa.

What is D-Mannose?

D-mannose is a simple sugar that plays a special role in metabolism through its involvement in the glycosylation of certain proteins. D-mannose is rapidly absorbed and reaches the peripheral organs in about 30 minutes, then is excreted through the urinary system. It cannot be converted into glycogen, so it is not stored in the body. It attaches to lectins and thus prevents the adhesion of pathogenic organisms to the walls of the bladder.

Mechanism of Action

Its mechanism of action is expressed through the inhibition of the adhesion of the surface protein FimH. By directly binding FimH to D-mannose, which is linked to a carrier protein responsible for receptor specificity.

The first stage of adhesion involves the mannose-sensitive binding of FimH to the epithelium. The wall of the urinary bladder is coated with various proteins glycosylated with mannose, such as the Tamm-Horsfall protein (THP), which directly interferes with the adhesion of microbes to the mucosa. The Tamm-Horsfall protein (THP) can bind to E. Coli with a specific bond, which can be inhibited by exogenous D-mannose.

By inhibiting the adhesion of microbes to the epithelium of the urinary tract, D-mannose mimics the function of the epithelial barrier of the urinary tract.

Instructions for Use

Take 1 to 2 capsules per day.

Nutritional Value & Ingredients

1 to 2 capsules provide on average:

  • D-Mannose 500 - 1000 mg
  • Bearberry Leaf Extract (bearberry / uva-ursi) 20 - 40 mg
    • containing 10% arbutin 2 - 4 mg

Other ingredients: anti-caking agents: silicon dioxide, magnesium stearate, capsule: hydroxypropylmethylcellulose

Manufacturer

See full description

Specifications

Specifications

Product Details

Action [Health multiple]
Urinary
Active Substance
D-Mannose
Meal Replacement
No
Kid's
No

Quantity

Capsules
60 caps

Important information

Specifications are collected from official manufacturer websites. Please verify the specifications before proceeding with your final purchase. If you notice any problem you can report it here.

See all specifications

Reviews (147)

Reviews

  1. 122
  2. 15
  3. 4
  4. 3
  5. 3
Review this product

Reviews by our members

  • nektarini46
    4
    0 out of 1 members found this review helpful

    For urinary tract infections caused by E. coli, it helps. Otherwise, try high-purity Meth. Blue to be permanently free from urological issues.

    Translated from Greek ·
    Did you find this review helpful?
  • Kelly87
    1
    0 out of 1 members found this review helpful

    Verified purchase

    It did nothing for me. The other product, the enhanced one, was much better. With that, I would take one capsule. Maybe I should have taken two. I will not buy it again.

    Translated from Greek ·
    • Effectiveness
    • I would not buy it again
    Did you find this review helpful?
  • konstz
    4
    2 out of 2 members found this review helpful

    Verified purchase

    This review is about the quantity: 90 caps

    I have been taking it daily for quite some time now in combination with cranberry, and I can say that it has helped with bladder function, especially at night, so I don’t need to get up more than once, even if I drink an incredible amount of water.

    However, I didn’t escape epididymitis, and suddenly one morning my right testicle appeared swollen and I was scared because I didn’t know what it was about.

    I informed the doctor about the symptoms—pain, fever, flushed testicle—and he prescribed antibiotics. I am still on my fifth pill. I have a long way to go. I continue to take the supplements because they also have a therapeutic effect. I will provide another update later.

    Translated from Greek ·
    • I would buy it again
    • Effectiveness
    Did you find this review helpful?
  • Elena_Theocharous
    5
    8 out of 8 members found this review helpful

    Verified purchase

    I take 1 pill a day as a preventive measure after recurring urinary infections and I am quite satisfied combining it with cranberry pills.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • itsathina
    5
    3 out of 3 members found this review helpful

    Verified purchase

    This review is about the quantity: 90 caps

    It's not for more than 2 months in a row. Very good product. It helped me a lot with the recurring urinary infections.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Eva Maria Kazantzoglou
    5
    8 out of 8 members found this review helpful

    Verified purchase

    Great for those who often suffer from urinary tract infections. At the first symptom, I take it and avoid antibiotics.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • itsathina
    5
    12 out of 12 members found this review helpful

    Verified purchase

    I got it due to recurring urinary tract infections.. on days when I feel discomfort and after intercourse, I take two, otherwise one per day. I haven't had a reinfection for 4 months.

    **Update: I haven't had a reinfection for 15 months**

    The side effects of D-mannose may include bloating, something I did not notice with this supplement, compared to another well-known brand.

    You should be careful about using D-mannose if you are pregnant or breastfeeding, because there hasn't been enough research on its safety in these cases, and it is also reported to prevent conception by stopping sperm from penetrating the egg. Do your research.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Athinaki_Nt
    5
    7 out of 8 members found this review helpful

    Verified purchase

    These vitamins really do what they promise. I was suffering from recurrent urinary tract infections and since I started taking one tablet a day, there has been no recurrence. In consultation with my doctor, she approved this product and told me that it has dramatic results.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • mariannanefeli2
    5
    12 out of 12 members found this review helpful

    It saved me from urinary tract infections... Every 2 months I would get a urinary tract infection and as a result, I would constantly take antibiotics.... Since I started using it 3 months ago, I have no discomfort at all.... Miraculous... It saved me

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • hrwstefanaki
    5
    19 out of 19 members found this review helpful

    Verified purchase

    If I had to put only one product in the entire Skrouz with 5 stars, I would put it in this one. It changed my life. 12 years of long-term treatments for cystitis and nothing. I always had problems. Since my uncle introduced it to me 2 years ago, I have forgotten what a urinary tract infection is.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • vasanem
    5
    39 out of 39 members found this review helpful

    D Mannose, L Cysteine, probiotics, a good cranberry supplement, attention to vaginal dryness that exacerbates predisposition, and a mix of vitamins for urinary health, and finally after many years of conventional medical treatments that did little, I found a permanent solution to urinary tract infections and I relaxed. I'm sorry that the medical community is so uncompromising in some approaches, I hope this changes.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • nana11
    5
    12 out of 12 members found this review helpful

    Verified purchase

    Excellent and at a very good price, I take 1 capsule daily (plus 1 after each contact whenever it happens) for the prevention of recurrent urinary tract infections and it has saved me after a chronic problem with recurring urinary tract infections (e-coli).

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • atouranakou
    5
    23 out of 24 members found this review helpful

    For those who suffer from frequent urinary tract infections, especially from the most "popular" e. Coli, this substance is amazing. I have been treating my cystitis without antibiotics anymore. However, I want to emphasize that 2gr per day are needed for real protection-treatment, meaning 4 pills and of course, with plenty of water.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Katerina80!!
    5
    15 out of 15 members found this review helpful

    Verified purchase

    Frequent minor annoyances have ceased to exist. Certain help for those experiencing such symptoms.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Nikkiv
    5
    16 out of 16 members found this review helpful

    Verified purchase

    The mother who suffered from urinary tract infections has been using it for two years and hasn't taken antibiotics again!

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Verified purchase

    It really helps. It saved me from needing antibiotics.

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    helps a lot to avoid urinary tract infection

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 90 caps

    the best supplements, they help me prevent urinary tract infections

    Translated from Greek ·
    Did you find this review helpful?
  • 5
    1 out of 1 members found this review helpful

    Verified purchase

    This review is about the quantity: 90 caps

    I am very satisfied because I have avoided many urinary tract infections

    Translated from Greek ·
    Did you find this review helpful?
  • This review is about the quantity: 30 caps

    Personally, it did not help me at all with urinary tract infection symptoms

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 90 caps

    Reliable and effective

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 30 caps

    It helps a lot in the prevention of constant urinary infections.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • unique product

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Verified purchase

    It does an amazing job

    Translated from Greek ·
    Did you find this review helpful?
  • 5
    1 out of 1 members found this review helpful

    Verified purchase

    This review is about the quantity: 30 caps

    In a urinary infection of my wife, the tests showed that it helped.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • 1
    1 out of 3 members found this review helpful
    This review is about the quantity: 30 caps

    While taking one tablet in the morning and one tablet in the evening for a month, I developed a urinary infection.

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 90 caps

    Effective product.

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    Saves from urinary tract infections

    Translated from Greek ·
    Did you find this review helpful?
  • 3
    1 out of 1 members found this review helpful

    Verified purchase

    suitable for urinary tract infections...

    Translated from Greek ·
    • I would buy it again
    Did you find this review helpful?
  • Verified purchase

    We now purchase it on a monthly basis as it seems to help with the condition.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • For urinary tract infections caused by E. coli, it helps. Otherwise, try high-purity Meth. Blue to be permanently free from urological issues.

    Translated from Greek ·
    0
  • It did nothing for me. The other product, the enhanced one, was much better. With that, I would take one capsule. Maybe I should have taken two. I will not buy it again.

    Translated from Greek ·
    0
  • I have been taking it daily for quite some time now in combination with cranberry, and I can say that it has helped with bladder function, especially at night, so I don’t need to get up more than once, even if I drink an incredible amount of water.

    However, I didn’t escape epididymitis, and suddenly one morning my right testicle appeared swollen and I was scared because I didn’t know what it was about.

    I informed the doctor about the symptoms—pain, fever, flushed testicle—and he prescribed antibiotics. I am still on my fifth pill. I have a long way to go. I continue to take the supplements because they also have a therapeutic effect. I will provide another update later.

    Translated from Greek ·
    2
  • I take 1 pill a day as a preventive measure after recurring urinary infections and I am quite satisfied combining it with cranberry pills.

    Translated from Greek ·
    8
  • It's not for more than 2 months in a row. Very good product. It helped me a lot with the recurring urinary infections.

    Translated from Greek ·
    3
  • See all

Description & Specifications

Dietary supplement containing the monosaccharide D-mannose and bearberry extract. Mannose is used for urinary tract infections, such as cystitis, while bearberry contributes to the normal function of the urinary system and bladder. It helps in the prevention and relief of initial symptoms by preventing bacteria from adhering to the mucosa.

What is D-Mannose?

D-mannose is a simple sugar that plays a special role in metabolism through its involvement in the glycosylation of certain proteins. D-mannose is rapidly absorbed and reaches the peripheral organs in about 30 minutes, then is excreted through the urinary system. It cannot be converted into glycogen, so it is not stored in the body. It attaches to lectins and thus prevents the adhesion of pathogenic organisms to the walls of the bladder.

Mechanism of Action

Its mechanism of action is expressed through the inhibition of the adhesion of the surface protein FimH. By directly binding FimH to D-mannose, which is linked to a carrier protein responsible for receptor specificity.

The first stage of adhesion involves the mannose-sensitive binding of FimH to the epithelium. The wall of the urinary bladder is coated with various proteins glycosylated with mannose, such as the Tamm-Horsfall protein (THP), which directly interferes with the adhesion of microbes to the mucosa. The Tamm-Horsfall protein (THP) can bind to E. Coli with a specific bond, which can be inhibited by exogenous D-mannose.

By inhibiting the adhesion of microbes to the epithelium of the urinary tract, D-mannose mimics the function of the epithelial barrier of the urinary tract.

Instructions for Use

Take 1 to 2 capsules per day.

Nutritional Value & Ingredients

1 to 2 capsules provide on average:

  • D-Mannose 500 - 1000 mg
  • Bearberry Leaf Extract (bearberry / uva-ursi) 20 - 40 mg
    • containing 10% arbutin 2 - 4 mg

Other ingredients: anti-caking agents: silicon dioxide, magnesium stearate, capsule: hydroxypropylmethylcellulose

Manufacturer

Product Details

Action [Health multiple]
Urinary
Active Substance
D-Mannose
Meal Replacement
No
Kid's
No

Quantity

Capsules
60 caps

Important information

Specifications are collected from official manufacturer websites. Please verify the specifications before proceeding with your final purchase. If you notice any problem you can report it here.

Reviews (147)

  1. 122
  2. 15
  3. 4
  4. 3
  5. 3
Review this product

Reviews by our members

  • nektarini46
    4
    0 out of 1 members found this review helpful

    For urinary tract infections caused by E. coli, it helps. Otherwise, try high-purity Meth. Blue to be permanently free from urological issues.

    Translated from Greek ·
    Did you find this review helpful?
  • Kelly87
    1
    0 out of 1 members found this review helpful

    Verified purchase

    It did nothing for me. The other product, the enhanced one, was much better. With that, I would take one capsule. Maybe I should have taken two. I will not buy it again.

    Translated from Greek ·
    • Effectiveness
    • I would not buy it again
    Did you find this review helpful?
  • konstz
    4
    2 out of 2 members found this review helpful

    Verified purchase

    This review is about the quantity: 90 caps

    I have been taking it daily for quite some time now in combination with cranberry, and I can say that it has helped with bladder function, especially at night, so I don’t need to get up more than once, even if I drink an incredible amount of water.

    However, I didn’t escape epididymitis, and suddenly one morning my right testicle appeared swollen and I was scared because I didn’t know what it was about.

    I informed the doctor about the symptoms—pain, fever, flushed testicle—and he prescribed antibiotics. I am still on my fifth pill. I have a long way to go. I continue to take the supplements because they also have a therapeutic effect. I will provide another update later.

    Translated from Greek ·
    • I would buy it again
    • Effectiveness
    Did you find this review helpful?
  • Elena_Theocharous
    5
    8 out of 8 members found this review helpful

    Verified purchase

    I take 1 pill a day as a preventive measure after recurring urinary infections and I am quite satisfied combining it with cranberry pills.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • itsathina
    5
    3 out of 3 members found this review helpful

    Verified purchase

    This review is about the quantity: 90 caps

    It's not for more than 2 months in a row. Very good product. It helped me a lot with the recurring urinary infections.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Eva Maria Kazantzoglou
    5
    8 out of 8 members found this review helpful

    Verified purchase

    Great for those who often suffer from urinary tract infections. At the first symptom, I take it and avoid antibiotics.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • itsathina
    5
    12 out of 12 members found this review helpful

    Verified purchase

    I got it due to recurring urinary tract infections.. on days when I feel discomfort and after intercourse, I take two, otherwise one per day. I haven't had a reinfection for 4 months.

    **Update: I haven't had a reinfection for 15 months**

    The side effects of D-mannose may include bloating, something I did not notice with this supplement, compared to another well-known brand.

    You should be careful about using D-mannose if you are pregnant or breastfeeding, because there hasn't been enough research on its safety in these cases, and it is also reported to prevent conception by stopping sperm from penetrating the egg. Do your research.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Athinaki_Nt
    5
    7 out of 8 members found this review helpful

    Verified purchase

    These vitamins really do what they promise. I was suffering from recurrent urinary tract infections and since I started taking one tablet a day, there has been no recurrence. In consultation with my doctor, she approved this product and told me that it has dramatic results.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • mariannanefeli2
    5
    12 out of 12 members found this review helpful

    It saved me from urinary tract infections... Every 2 months I would get a urinary tract infection and as a result, I would constantly take antibiotics.... Since I started using it 3 months ago, I have no discomfort at all.... Miraculous... It saved me

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • hrwstefanaki
    5
    19 out of 19 members found this review helpful

    Verified purchase

    If I had to put only one product in the entire Skrouz with 5 stars, I would put it in this one. It changed my life. 12 years of long-term treatments for cystitis and nothing. I always had problems. Since my uncle introduced it to me 2 years ago, I have forgotten what a urinary tract infection is.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • vasanem
    5
    39 out of 39 members found this review helpful

    D Mannose, L Cysteine, probiotics, a good cranberry supplement, attention to vaginal dryness that exacerbates predisposition, and a mix of vitamins for urinary health, and finally after many years of conventional medical treatments that did little, I found a permanent solution to urinary tract infections and I relaxed. I'm sorry that the medical community is so uncompromising in some approaches, I hope this changes.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • nana11
    5
    12 out of 12 members found this review helpful

    Verified purchase

    Excellent and at a very good price, I take 1 capsule daily (plus 1 after each contact whenever it happens) for the prevention of recurrent urinary tract infections and it has saved me after a chronic problem with recurring urinary tract infections (e-coli).

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • atouranakou
    5
    23 out of 24 members found this review helpful

    For those who suffer from frequent urinary tract infections, especially from the most "popular" e. Coli, this substance is amazing. I have been treating my cystitis without antibiotics anymore. However, I want to emphasize that 2gr per day are needed for real protection-treatment, meaning 4 pills and of course, with plenty of water.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Katerina80!!
    5
    15 out of 15 members found this review helpful

    Verified purchase

    Frequent minor annoyances have ceased to exist. Certain help for those experiencing such symptoms.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Nikkiv
    5
    16 out of 16 members found this review helpful

    Verified purchase

    The mother who suffered from urinary tract infections has been using it for two years and hasn't taken antibiotics again!

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Verified purchase

    It really helps. It saved me from needing antibiotics.

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    helps a lot to avoid urinary tract infection

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 90 caps

    the best supplements, they help me prevent urinary tract infections

    Translated from Greek ·
    Did you find this review helpful?
  • 5
    1 out of 1 members found this review helpful

    Verified purchase

    This review is about the quantity: 90 caps

    I am very satisfied because I have avoided many urinary tract infections

    Translated from Greek ·
    Did you find this review helpful?
  • This review is about the quantity: 30 caps

    Personally, it did not help me at all with urinary tract infection symptoms

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 90 caps

    Reliable and effective

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 30 caps

    It helps a lot in the prevention of constant urinary infections.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • unique product

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • Verified purchase

    It does an amazing job

    Translated from Greek ·
    Did you find this review helpful?
  • 5
    1 out of 1 members found this review helpful

    Verified purchase

    This review is about the quantity: 30 caps

    In a urinary infection of my wife, the tests showed that it helped.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • 1
    1 out of 3 members found this review helpful
    This review is about the quantity: 30 caps

    While taking one tablet in the morning and one tablet in the evening for a month, I developed a urinary infection.

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    This review is about the quantity: 90 caps

    Effective product.

    Translated from Greek ·
    Did you find this review helpful?
  • Verified purchase

    Saves from urinary tract infections

    Translated from Greek ·
    Did you find this review helpful?
  • 3
    1 out of 1 members found this review helpful

    Verified purchase

    suitable for urinary tract infections...

    Translated from Greek ·
    • I would buy it again
    Did you find this review helpful?
  • Verified purchase

    We now purchase it on a monthly basis as it seems to help with the condition.

    Translated from Greek ·
    • Effectiveness
    • I would buy it again
    Did you find this review helpful?
  • For urinary tract infections caused by E. coli, it helps. Otherwise, try high-purity Meth. Blue to be permanently free from urological issues.

    Translated from Greek ·
    0
  • It did nothing for me. The other product, the enhanced one, was much better. With that, I would take one capsule. Maybe I should have taken two. I will not buy it again.

    Translated from Greek ·
    0
  • I have been taking it daily for quite some time now in combination with cranberry, and I can say that it has helped with bladder function, especially at night, so I don’t need to get up more than once, even if I drink an incredible amount of water.

    However, I didn’t escape epididymitis, and suddenly one morning my right testicle appeared swollen and I was scared because I didn’t know what it was about.

    I informed the doctor about the symptoms—pain, fever, flushed testicle—and he prescribed antibiotics. I am still on my fifth pill. I have a long way to go. I continue to take the supplements because they also have a therapeutic effect. I will provide another update later.

    Translated from Greek ·
    2
  • I take 1 pill a day as a preventive measure after recurring urinary infections and I am quite satisfied combining it with cranberry pills.

    Translated from Greek ·
    8
  • It's not for more than 2 months in a row. Very good product. It helped me a lot with the recurring urinary infections.

    Translated from Greek ·
    3
  • See all
16,47 €
14,00 €   shipping cost