Rin and her immortal bodyguard have taken different paths, as she tries to find and avenge the murderer of her parents, the leader of Itto-Ryu, Anotsu Kagehisa. Meanwhile, Manji is recovering from his last -devastating- encounter with three members of Itto-Ryu and immediately sets off to find Rin. Both their allies and enemies are regrouping. Itto-Ryu makes its own moves and prepares to take revenge on those who have been hunting them for so long, while at the same time an old acquaintance makes his appearance at the doorstep of the Hyakurin gang...