The niacin has been recognized to help reduce cholesterol and aid in the prevention of cardiovascular diseases. Studies have shown that niacin lowers LDL (bad cholesterol). Taking niacin usually causes redness on the body and face. Life Extension's "No Flush" niacin contains a special form of niacin, inositol hexanicotinate. This is an ester derivative of niacin and inositol in a ratio (6:1). This derivative allows niacin to act without causing the unpleasant side effect of redness. Inositol is another B-complex vitamin that helps in the metabolism of fats in the liver and the function of neurons.