Genetic disorders are known to affect the way the brain develops, its structure, and its function, with subsequent impacts on neurocognitive functions, academic performance, and the individual's behavior. Despite our knowledge of external and genetic characteristics, psychopathology, and comorbidities faced by these individuals, the available literature on the relationship between the brain and the observed deficits in learning and behavior remains limited.

For this reason, the present collective volume focuses on describing the cognitive and behavioral phenotype exhibited by various genetic syndromes through reviewing studies in clinical neuropsychology and neuroimaging, as well as case studies. Among the syndromes described are both well-known and rarer syndromes due to chromosomal abnormalities, monogenic mutations, genetic material deficits, and genomic imprinting disorders.

Consequently, this volume serves as a valuable source of information for students, educators, psychologists, doctors, and other professionals in special education and health, enabling them to recognize and differentiate the behavioral profiles of individuals with genetic syndromes based on the neuropsychological profiles they present.

Finally, all contemporary methods related to diagnosis and interventions are described, with an emphasis primarily on managing the neurocognitive deficits of individuals with genetic syndromes.

Contents

• Foreword by the editors
• Introduction to the neuropsychology of genetic syndromes related to intellectual disability from the perspective of the Developmental Approach
• Clinical neuropsychological assessment in individuals with genetic syndromes illustrated through a case study
• Neurology and neuroimaging in genetic syndromes
• Down syndrome
• Trisomy 18 (Edwards syndrome)
• Patau syndrome
• Klinefelter syndrome
• Pallister-Killian syndrome
• Noonan syndrome
• Neurofibromatosis type 1
• Tuberous sclerosis
• Fragile X syndrome
• Rett syndrome
• Cornelia de Lange syndrome
• Apert syndrome
• Rubinstein-Taybi syndrome
• Lesch-Nyhan syndrome
• Alexander syndrome
• 22q11.2 microdeletion syndrome (DiGeorge syndrome)
• Williams-Beuren syndrome
• Smith-Magenis syndrome
• Cri du Chat syndrome
• Prader-Willi syndrome
• Angelman syndrome