I have been taking St. John's Wort from this specific company for about a year now, with some breaks, and I can say with certainty that it has helped me a lot in reducing anxiety, tension, worry, and mild depression. After I stopped the treatment (11 months) with antidepressants for generalized anxiety disorder and depression, St. John's Wort has been the best for keeping me stable. Although I do not recommend it for long-term use (and personally I plan to stop it) because it has side effects that I will mention below. I see results after 2-3 weeks of use. At the beginning of the treatment, I took two a day for two weeks. Then I switched to one normally. Although the recommended dose is 1 a day, I did it to act more quickly. Also, it is a good combination with Rhodiola Rosea and a multivitamin with antioxidants, digestive enzymes & amino acids to support the body. The effectiveness of Rhodiola Rosea does not last long; it is for the beginning of the treatment. For severe depression and anxiety, I suggest you visit a psychiatrist or psychologist; they will decide if medication is necessary and of course psychotherapy. Be careful not to combine it with antidepressants because they have similar effects and can cause serious side effects. However, there are also its negatives. Its use causes photosensitivity and skin sensitivity, even damage to the eyes. It sounds concerning, and searching forums with users around the world, they report having problems. Personally, I have noticed sensitivity to light. An alternative to St. John's Wort is 5HTP and SAMe. I plan to try them.