From 189 it reached 350. Unfortunately, it doesn't help me replenish to the extent needed, only when combined with dairy products, especially sour milk. There I noticed better absorption, but again, not sufficient because the symptoms of exhaustion are quite intense. So today I had to take my first B12 injection and personally I recommend it for cost reasons, BUT MOSTLY FOR MORE EFFECTIVE PROBLEM SOLVING. After consulting my pathologist, I got it from a friend who is a pharmacist and it didn't cost more than 3-4 euros... I will do the other two injections every following week. A total of 3 injections.. Conclusion = Better injection. You will solve the problem. Note = Even if B12 is 450, you can still have symptoms as my gastroenterologist told me and my pathologist confirmed. So it is not beneficial to consume it in expenses and physical discomfort. You can simply take it in pill form as a supplement, depending on the problem or the periodic examination you will have every 6 months after the injection is administered... Meaning after the injections, the vitamin can reach up to 2000 units... It is considered a normal progression after the administration of the injections. After 6 months, do a re-examination and usually people who have a chronic B12 deficiency problem usually [as my microbiologist told me] if it drops from 2000 to 800-600, then in three months they repeat the treatment with the injections... However, if you have not yet identified if the problem is chronic, then repeat the examination and if you find another deficiency, it would be good to investigate if you have metabolic syndrome or any other condition or nutritional disorder.