Cross Academy hosts two groups of students: the Day Class and the Night Class. At dusk, when the Day Class students return to their dorms, they encounter the Night Class on their way to school. Yuki Cross and Zero Kiryu are the Guardians of the academy, protecting the Day Class from the dark secret of the Academy: the Night Class is full of vampires!

Yukio and Zero team up to hunt Kaname. Yuki and Kaname fight at the base of the Hunter Society while Sara tries to control Zero through her blood. The metallic material of the female ancestral intervention appears, and Yuki realizes that there is only one way to stop Kaname…