Diamine oxidase (DAO) is an important enzyme produced in the digestive system, specifically in the small intestine, and serves as a natural defense against excess histamine. DAO deficiency involves the lack of the enzyme in the intestine, affecting 15% of the population, mainly women.

When there is DAO deficiency, histamine accumulates in the blood plasma, leading to unwanted side effects.

Causes of DAO deficiency may include:

• Hereditary factors, such as genetic alterations.
• Pharmacological reasons: A total of 90 common drugs, such as analgesics, antihistamines, antidepressants, antihypertensives, diuretics, and gastroprotective agents, affect the enzyme's action.
• Alcohol consumption.
• Inflammatory bowel diseases.

Indications:

• Treatment of problems caused by diamine oxidase deficiency.
• Migraine, headache, dizziness.
• Irritable bowel syndrome.
• Nasal congestion.
• Asthma.
• Urticaria.
• Chronic fatigue.
• Fibromyalgia.
• Atopic dermatitis.
• Degenerative osteopathy.

Dosage: 1 capsule 15-20 minutes before a main meal. Maximum dosage is 3 capsules per day.

Packaging: Each package contains 30 capsules.