R404A is a blend of hydrofluorocarbons that is used in low and medium temperature cooling applications, such as those employed in commercial refrigeration, industrial refrigeration, and transport refrigeration.

It is ideal for refrigeration performance at low evaporation temperatures and has advantages in freezing installations.

The application of this refrigerant requires careful attention as it is subject to the restrictions of the F-gas regulation effective from January 1, 2020.