Regenerative medicine is a promising and pioneering branch of medicine that has made impressive inroads into clinical practice in recent years. It successfully integrates the fields of tissue biomechanics, cellular, developmental and molecular biology, biomaterials science, gene editing, and nanotechnology, playing a crucial role in the therapeutic treatment of genetic and acquired diseases. It has direct applications in the repair and restoration of tissues and organs, as well as in the development of therapies for numerous diseases.
This manual describes the molecular, mechanistic, and phenotypic properties of stem cells and the extracellular matrix, focusing on the key factors of tissue formation. It also presents the role of biomaterials in regenerative medicine and covers cutting-edge technologies in the field, including gene editing, preclinical models, bioreactors, and bioprinters. Additionally, therapeutic applications for specific types of tissues and organs are examined. Finally, extensive reference is made to the regulatory, political, and ethical aspects of regenerative medicine.
This work is aimed at students (medicine, biology, pharmacy, dentistry, and other sciences), as well as researchers, clinical physicians, postdoctoral scientists, healthcare professionals, and the broader reading public interested in learning about this particular field.
