With FRIO cases, you can keep insulin or other medications at 18-26°C for at least 45 hours without ice. It offers freedom in your travels and withstands warm environments. It is very easy to use, reusable, and has long-lasting durability. The FRIO travel wallet is designed to keep insulin and other medications cool and at safe temperatures from 18-26°C even in a stable ambient temperature of 37.8°C. Simply activate it with cold water for the required time depending on the size of the wallet. The FRIO Cooling Wallet consists of two parts: the inner cooling wallet and the outer Cambrelle cover which protects the inner cooling wallet.